Voices of Cherokee Women is a compelling collection of first-person accounts by Cherokee women. It includes letters, diaries, newspaper articles, oral histories, ancient myths, and accounts by travelers, traders, and missionaries who encountered the Cherokees from the 16th century to the present. Among the stories told by these "voices" are those of Rebecca Neugin being carried as a child on the Trail of Tears; Mary Stapler Ross seeing her beautiful Rose Cottage burned to the ground during the Civil War; Hannah Hicks watching as marauders steal her food and split open her feather beds, scattering the feathers in the wind; and girls at the Cherokee Female Seminary studying the same curriculum as women at Mount Holyoke.

Voices of Cherokee Women recounts how Cherokee women went from having equality within the tribe to losing much of their political and economic power in the 19th century to regaining power in the 20th, as Joyce Dugan and Wilma Mankiller became the first female chiefs of the Cherokee Nation. The book's publication is timed for the commemoration of the 175th anniversary of the Trail of Tears.